Atom vs Molecule: What Is the Difference?

An atom is the smallest piece of an element. A molecule is two or more atoms joined by chemical bonds. One oxygen atom on its own is an atom. Two oxygen atoms bonded together make an oxygen molecule, O2, the oxygen you breathe.

Oxygen atom in the 3D Periodic Table

Atom

One oxygen atom: a nucleus with 8 protons and 8 electrons around it.

Oxygen molecule O2 in 3D

Molecule

Two oxygen atoms bonded together: O2.

Atom vs molecule at a glance

AtomMolecule
What it isThe smallest piece of an elementTwo or more atoms joined by chemical bonds
Made ofProtons, neutrons and electronsAtoms
ExampleOne oxygen atom, OAn oxygen molecule, O2, or water, H2O
SizeAbout 0.1 to 0.5 nm acrossFrom about 0.2 nm to many nanometres
Kinds118 known elementsMillions of different molecules
Can be split by chemistryNoYes, into its atoms

Inside an atom

Every atom has a tiny nucleus of protons and neutrons, with electrons moving around it. The number of protons decides which element it is: 1 for hydrogen, 6 for carbon, 8 for oxygen. Almost all of an atom is empty space. If the nucleus were the size of a pea, the atom would be the size of a football stadium.

From atoms to molecules

Atoms bond by sharing or moving electrons. Two oxygen atoms share two pairs of electrons to make O2. Add two hydrogen atoms to one oxygen and you get water, H2O. A molecule made of different elements is also a compound. Some substances, such as table salt, are made of ions in a lattice rather than separate molecules.

Quick facts

  • Noble gases such as helium and neon exist as single atoms, not molecules.
  • A single drop of water holds around 1.7 sextillion molecules, 17 followed by 20 zeros.
  • Ozone, O3, is a molecule of three oxygen atoms.
  • The word atom comes from the Greek for uncuttable.
  • DNA molecules can contain billions of atoms.

See them in 3D

Water molecule in 3D
Water: one oxygen atom and two hydrogen atoms.
Hydrogen in the 3D Periodic Table
Hydrogen, the simplest atom: one proton and one electron.
Open the 3D Periodic Table All 3D molecules

Atom vs molecule questions

What is the difference between an atom and a molecule?

An atom is the smallest piece of an element. A molecule is two or more atoms chemically bonded together.

Is oxygen an atom or a molecule?

Both words are used. A single O is an oxygen atom. The oxygen gas we breathe is made of O2 molecules, two oxygen atoms bonded together.

Is water an atom or a molecule?

A molecule, made of two hydrogen atoms and one oxygen atom.

Are all molecules compounds?

No. A molecule of one element, such as O2, is not a compound. A molecule with two or more different elements, such as H2O, is.

What is smaller than an atom?

Protons, neutrons and electrons, and protons and neutrons are made of even smaller quarks.

More face-offs: see all 3D comparisons.

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